MicroLyte^® Ag Antimicrobial Matrix absorbs wound fluid and forms a soft gel that conforms to the wound surface and maintains a moist environment. The dressing contains silver only to prevent or minimize microbial growth within the dressing. MicroLyte^® Ag Matrix is so thin that it inherently conforms to the underlying contours of a moist wound-bed, providing intimate contact with the microbes on wound-bed. Antimicrobial silver in MicroLyte^® Ag Matrix kills bacteria that come into contact with the dressing, and reduces microbial colonization. This action reduces loss of silver in wound exudate and provides effective antimicrobial action at much lower silver concentrations. Reduction of bacterial bioburden may reduce microbial colonization and risks of wound infection.

Antimicrobial Efficacy

Unlike traditional antimicrobial dressings, Imbed’s ultrathin Microfilm™ technology enables MicroLyte^® Ag Matrix to conform intimately to the tissue of a wound bed. By exerting sustained antimicrobial activity of silver (Ag) for up to 72 h in the microscopic environment of the wound tissue, it kills > 99.99% CFU (colony forming units) of clinically relevant microbes at 100x lower level of antimicrobial silver compared to other dressings.

Biocompatibility

The biocompatibility profile of the MicroLyte^® Ag Matrix was assessed in accordance with ISO-10993: Biological Evaluations of Medical Devices. The biocompatibility test results demonstrate that MicroLyte^® Ag Matrix is biocompatible and safe for for use in management of partial and full thickness wounds including pressure ulcers, venous ulcers, diabetic ulcers, first and second degree burns, abrasions and lacerations, donor sites and surgical wounds, and debrided and grafted partial thickness wounds.

Antimicrobial dressings and matrices are vital to managing bioburden in stalled wounds, thus allowing normal healing to proceed. Increasingly, higher levels of silver are being used to achieve greater antimicrobial activity. These excessive levels of silver, however, result in severe staining of the wound and inhibit re-epithelialization due to tissue toxicity.

The technology behind the MicroLyte^® Ag Matrix results in an effective, yet gentle antimicrobial dressing. Unlike traditional silver dressings which are crude, high-capacity reservoirs of silver, MicroLyte^® Ag Matrix conforms to contours of underlying wound bed resulting in antimicrobial action in the local microscopic environment of the wound bed where microbes colonize, allowing silver to be effective at very low concentrations. Based on Imbed’s patented ultrathin Microfilm™ technology platform, the MicroLyte^® Ag Matrix is just 20 microns thick and it contains 10-500x less silver compared to the leading silver-based antimicrobial dressings. Yet the antimicrobial silver in MicroLyte^® Ag Matrix kills >99.99% of a broad spectrum of bacteria and yeast in contact with the matrix, including MRSA and VRE stains. Ionic and metallic silver in the matrix provides sustained antimicrobial activity for up to 3 days.

This reduces silver loss in wound exudate, and the associated toxicity, irritation, and costs, while increasing comfort for patients. MicroLyte^® Ag Matrix ultimately bioresorbs, thus eliminating the need for painful dressing removal.

No other product combines bioresorbability and antimicrobial activity in a fully synthetic matrix.

MicroLyte^® Ag Matrix is individually packaged in a sterile foil pouch a supplied sterile in boxes of 5 units. Sterilization by E-beam radiation. Sterility is guaranteed unless pouch is damaged or opened. Single use only.

REF. 91001- 2 inch x 2 inch (5 cm x 5 cm)
REF. 91002- 4 inch x 4 inch (10 cm x 10 cm)