Introducing
MicroLyte® Ag Antimicrobial Matrix
A One-of-a-Kind Combination
The all-new MicroLyte® Ag Antimicrobial Matrix brings a unique combination of characteristics in a wound care product.
Resorbable.
MicroLyte® Ag Matrix is an ultrathin, fully-synthetic contact dressing composed primarily of bioresorbable polyvinyl alcohol sheet with a polymeric surface coating containing ionic and metallic silver. The matrix maintains a physiologically moist microenvironment. This environment is conducive to granulation tissue formation, cell growth, and neovascularization. Because the matrix material is bioresorbable, the matrix never needs to be removed from the wound.
Antimicrobial.
MicroLyte® Ag Matrix contains antimicrobial silver in the matrix which kills bacteria in contact with the matrix and combats bacteria in deep wound tissue. Reduction of bacterial bioburden may reduce microbial colonization and risks of wound infection. The addition of both ionic and metallic silver provides rapid, effective, and sustained antimicrobial activity.
- 510k-cleared for 3-day antimicrobial effect
- >99.99% effective against a broad spectrum of wound-related microbes
The conformability of MicroLyte® Ag Matrix means that it remains highly effective even with low amounts of silver, translating to:
- Less wound staining
- Lower residual tissue toxicity
Fully Synthetic.
Because MicroLyte® Ag Matrix is 100% synthetic there is no chance of disease transmission from animal-derived products.
The combination of these characteristics allows MicroLyte® Ag Matrix to be your first choice in wound care.
Mechanism of Action
MicroLyte® Ag Antimicrobial Matrix absorbs wound fluid and forms a soft gel that conforms to the wound surface and maintains a moist environment. The dressing contains silver only to prevent or minimize microbial growth within the dressing. MicroLyte® Ag Matrix is so thin that it inherently conforms to the underlying contours of a moist wound-bed, providing intimate contact with the microbes on wound-bed. Antimicrobial silver in MicroLyte® Ag Matrix kills bacteria that come into contact with the dressing, and reduces microbial colonization. This action reduces loss of silver in wound exudate and provides effective antimicrobial action at much lower silver concentrations. Reduction of bacterial bioburden may reduce microbial colonization and risks of wound infection.
Safety and Efficacy
Antimicrobial Efficacy
Unlike traditional antimicrobial dressings, Imbed’s ultrathin Microfilm™ technology enables MicroLyte® Ag Matrix to conform intimately to the tissue of a wound bed. By exerting sustained antimicrobial activity of silver (Ag) for up to 72 h in the microscopic environment of the wound tissue, it kills > 99.99% CFU (colony forming units) of clinically relevant microbes at 100x lower level of antimicrobial silver compared to other dressings.
Learn MoreBiocompatibility
The biocompatibility profile of the MicroLyte® Ag Matrix was assessed in accordance with ISO-10993: Biological Evaluations of Medical Devices. The biocompatibility test results demonstrate that MicroLyte® Ag Matrix is biocompatible and safe for for use in management of partial and full thickness wounds including pressure ulcers, venous ulcers, diabetic ulcers, first and second degree burns, abrasions and lacerations, donor sites and surgical wounds, and debrided and grafted partial thickness wounds.
Learn MoreMicroLyte® Ag Matrix vs. Traditional Wound Dressings and Matrices
Antimicrobial dressings and matrices are vital to managing bioburden in stalled wounds, thus allowing normal healing to proceed. Increasingly, higher levels of silver are being used to achieve greater antimicrobial activity. These excessive levels of silver, however, result in severe staining of the wound and inhibit re-epithelialization due to tissue toxicity.
The technology behind the MicroLyte® Ag Matrix results in an effective, yet gentle antimicrobial dressing. Unlike traditional silver dressings which are crude, high-capacity reservoirs of silver, MicroLyte® Ag Matrix conforms to contours of underlying wound bed resulting in antimicrobial action in the local microscopic environment of the wound bed where microbes colonize, allowing silver to be effective at very low concentrations. Based on Imbed’s patented ultrathin Microfilm™ technology platform, the MicroLyte® Ag Matrix is just 20 microns thick and it contains 10-500x less silver compared to the leading silver-based antimicrobial dressings. Yet the antimicrobial silver in MicroLyte® Ag Matrix kills >99.99% of a broad spectrum of bacteria and yeast in contact with the matrix, including MRSA and VRE stains. Ionic and metallic silver in the matrix provides sustained antimicrobial activity for up to 3 days.
This reduces silver loss in wound exudate, and the associated toxicity, irritation, and costs, while increasing comfort for patients. MicroLyte® Ag Matrix ultimately bioresorbs, thus eliminating the need for painful dressing removal.
No other product combines bioresorbability and antimicrobial activity in a fully synthetic matrix.
Indications for Use
MicroLyte® Ag Matrix is indicated for the management of wounds and can be used over-the-counter for minor wounds such as abrasions and lacerations, minor cuts, and minor scalds and burns. Under the direction of a healthcare professional, MicroLyte® Ag Matrix may be used for more serious wounds such as partial and full thickness pressure ulcers, venous stasis ulcers, diabetic ulcers, first and second degree burns, abrasions and lacerations, donor sites and surgical wounds. MicroLyte® Ag Matrix may be used over debrided and grafted partial thickness wounds.

Chronic Wounds
Diabetic Foot Ulcers, Venous Leg Ulcers, Pressure Ulcers

Burns
First and Second Degree Burns

Surgical Wounds
Surgical Incisions, Moh’s Surgery, Reconstruction Surgery

Skin Grafts
Donor Sites, Debrided and Grafted Partial Thickness Wounds
TOP
“Less silver is more effective for wound management. MicroLyte® Ag Matrix has realized that paradigm shift in practice.”
– Dr. Michael J. Schurr, MD (Inventor)
Product Application
MicroLyte® Ag Matrix is easy to apply. Once removed from its pouch and placed on a moist wound bed, MicroLyte® Ag Matrix immediately begins to hydrate and conform to the fine contours of the wound bed. Within seconds, the dressing has completely adhered to the wound and can be covered with the secondary dressing preferred for a given wound.
To reapply, carefully remove the secondary cover dressing. Gently irrigate wound with sterile saline to remove necrotic tissue. It is not necessary to remove any residual MicroLyte® Ag Matrix observed during secondary cover dressing changes.
Product Specifications
MicroLyte® Ag Matrix is individually packaged in a sterile foil pouch a supplied sterile in boxes of 5 units. Sterilization by E-beam radiation. Sterility is guaranteed unless pouch is damaged or opened. Single use only.
REF. 91001- 2 inch x 2 inch (5 cm x 5 cm)
REF. 91002- 4 inch x 4 inch (10 cm x 10 cm)
Latest News
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April 4, 2017
Madison, WI, April 4, 2017 – Imbed Biosciences, a developer of advanced biomaterials and wound…
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September 9, 2016
Madison, WI, September 9, 2016 – Imbed Biosciences, a developer of advanced biomaterials and wound…
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August 5, 2016
MADISON, WI (Aug 5, 2016) – Imbed Biosciences announced today that it has received clearance…
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May 12, 2016
Bremen, Germany (May 12, 2016) – Imbed Biosciences announces that its microfilm wound dressing technology…