Introducing MicroLyte® Ag Wound Dressing

MicroLyte® Ag wound dressing is an ultrathin absorbent polyvinyl alcohol gelling fiber sheet with a polymeric surface coating containing ionic and metallic silver. It has very low amounts of silver, with a maximum of 0.4 mg of silver in a 2 inch x 2 inch dressing. It is only 20 microns thick and it contains 10 to 100 times less silver compared to the leading silver based wound dressings in the market.

Mechanism of Action

The dressing absorbs wound fluid and forms a soft gel that conforms to the wound surface and maintains a moist environment. The dressing contains silver only to prevent or minimize microbial growth within the dressing. MicroLyte® Ag is so thin that it inherently conforms to the underlying contours of a moist wound-bed, providing intimate contact with the microbes on wound-bed. Antimicrobial silver in the dressing kills bacteria that come into contact with the dressing, and reduces microbial colonization. This action reduces loss of silver in wound exudate and provides effective antimicrobial action at much lower silver concentrations.

Safety and Efficacy

Antimicrobial Efficacy

Unlike traditional antimicrobial dressings, Imbed’s ultrathin Microfilm™ technology enables MicroLyte® Ag wound dressing to conform intimately to the tissue of a wound bed. By exerting sustained antimicrobial activity of silver (Ag) for up to 72 h in the microscopic environment of the wound tissue, it kills > 99.99% CFU (colony forming units) of clinically relevant microbes at 100x lower level of antimicrobial silver compared to other dressings.

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Biocompatibility

The biocompatibility profile of the MicroLyte® Ag wound dressing was assessed in accordance with ISO-10993: Biological Evaluations of Medical Devices. The biocompatibility test results demonstrate that MicroLyte® Ag wound dressing is biocompatible and safe for for use in management of partial and full thickness wounds including pressure ulcers, venous ulcers, diabetic ulcers, first and second degree burns, abrasions and lacerations, donor sites and surgical wounds, and debrided and grafted partial thickness wounds.

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MicroLyte® Ag vs. Traditional Wound Dressings

Antimicrobial dressings are vital to clearing infections from stalled wounds thus allowing normal healing to proceed. Increasingly, higher levels of silver are being used to achieve greater effectiveness. This approach, however, inhibits re-epithelialization due to toxicity related to excessive silver and severe staining of the wound tissue.

The technology behind the MicroLyte® Ag wound dressing results in an effective, yet gentle antimicrobial dressing. Based on Imbed’s patented ultrathin Microfilm™ technology platform, the MicroLyte® Ag dressing is just 20 microns thick and it contains 10-500x less silver compared to the leading silver-based antimicrobial dressings. Yet the MicroLyte® Ag dressing kills >99.99% of clinically relevant microbes over 24 – 72 h, and allows normal healing of the wound.

Unlike traditional silver dressings which are crude, high-capacity reservoirs of silver, MicroLyte® Ag conforms to contours of underlying wound bed resulting in antimicrobial action in the local microscopic environment of the wound bed where microbes colonize, allowing silver to be effective at very low concentrations. This reduces silver loss in wound exudate, and the associated toxicity, irritation, and costs, while increasing comfort for patients. The dressing ultimately dissolves, thus eliminating the need for painful dressing removal.

Product Specifications

MicroLyte® Ag wound dressings are individually packaged in a sterile foil pouch. Supplied in boxes of individually packaged sterile dressings. Sterilization by E-beam radiation. Sterility is guaranteed unless pouch is damaged or opened. Single use only.

REF. 91001- 2 inch x 2 inch (5 cm x 5 cm)
REF. 91002- 4 inch x 4 inch (10 cm x 10 cm)

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Indications for Use

MicroLyte® Ag wound dressing is indicated for the management of wounds and can be used over-the-counter for minor wounds such as abrasions and lacerations, minor cuts, and minor scalds and burns. Under the direction of a healthcare professional, MicroLyte® Ag may be used for more serious wounds such as partial and full thickness pressure ulcers, venous stasis ulcers, diabetic ulcers, first and second degree burns, abrasions and lacerations, donor sites and surgical wounds. MicroLyte® Ag wound dressing may be used over debrided and grafted partial thickness wounds.

Chronic Wounds

Diabetic Foot Ulcers, Venous Leg Ulcers, Pressure Ulcers

Burns

First and Second Degree Burns

Surgical Wounds

Surgical Incisions, Moh’s Surgery, Reconstruction Surgery

Skin Grafts

Donor Sites, Debrided and Grafted Partial Thickness Wounds

TOP

“Less silver is more effective for wound management. MicroLyte® Ag has realized that paradigm shift in practice.”

– Dr. Michael J. Schurr, MD (Inventor)

Product Application

The MicroLyte® Ag wound dressing is easy to apply. Once removed from its pouch and placed on a moist wound bed, the MicroLyte® Ag dressing immediately begins to hydrate and conform to the fine contours of the wound bed. Within seconds, the dressing has completely adhered to the wound and can be covered with the secondary dressing preferred for a given wound.

Clinical Cases

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Latest News

  • SURPRISED AT THE
    IMPROVEMENT IN
    CHRONIC WOUNDS

    I was surprised at the improvement in chronic wounds that did not appear
    to have bacterial burden but were stalled in healing.
    It worked well in diabetic foot ulcers, especially under the
    total contact cast.
    General & Critical Care Surgeon, Mission Hospitals, Asheville, NC
  • SIMPLE TO USE -
    NO PREPERATION REQUIRED

    It is very simple to use- doesn’t require any preparation.
    Unlike other dressings that sit on top, Microlyte Ag visually conforms
    to wound surface and gives clear observation that it is getting to work.
    Visually more intimate contact with the wound than other dressings.
    Vascular Surgeon, University of North Carolina School of Medicine, Chapel Hill, NC
  • GENTLE APPLICATION
    NO PAIN
    EASE OF USE

    Patients and providers love that they can see the dressing getting
    to work at the application. Patients liked gentle application and lack
    of pain during dressing change. Providers like ease of use and application.
    Nurse Practitioner, Ascension-Ministry Saint Michael’s Hospital, Stevens Point, WI
  • LOW SILVER
    CONTENT

    Low silver content allows antimicrobial plus regenerative therapy
    at the same time. I can do it all at the same time.
    Vascular Surgeon, Mount Sinai Hospital, New York, NY
  • NOVEL AND UNIQUE
    NO STAINING
    NO PAIN

    The ultrathin transparent film architecture is novel and unique.
    We like that the dressing can be rinsed off the wound, but doesn’t have to be
    ‘dug out’ like other dressings. No silver presence or staining
    after application is attractive.
    Dermatologist & Cutaneous Surgeon, MD, University of Miami Hospital, Miami, FL
  • MY TEAM LOVES IT.

    We have trialed Microlyte Ag on three patients with amazing results. My team loves it.
    Plastic & Reconstructive Surgeon, University of Nebraska Medical Center