MicroLyte™ Ag VET wound dressing is an ultrathin absorbent polyvinyl alcohol hydrogel sheet with a polymeric surface coating containing ionic and metallic silver. It has very low amounts of silver, with a maximum of 0.4 mg of silver in a 2 inch x 2 inch dressing. It is only 20 microns thick and it contains 10 to 100 times less silver compared to the leading silver based wound dressings in the market.

Mechanism of Action

The dressing absorbs wound fluid and forms a soft gel that conforms to the wound surface and maintains a moist environment. The dressing contains silver only to prevent or minimize microbial growth within the dressing. MicroLyte™ Ag VET is so thin that it inherently conforms to the underlying contours of a moist wound-bed, providing intimate contact with the microbes on wound-bed. Antimicrobial silver in the dressing kills bacteria that come into contact with the dressing, and reduces microbial colonization. This action reduces loss of silver in wound exudate and provides effective antimicrobial action at much lower silver concentrations.

Safety and Efficacy

Antimicrobial Efficacy

Unlike traditional antimicrobial dressings, Imbed’s ultrathin Microfilm™ technology enables Microlyte™ Ag VET wound dressing to conform intimately to the tissue of a wound bed. By exerting sustained antimicrobial activity of silver (Ag) for up to 72 h in the microscopic environment of the wound tissue, it kills > 99.99% CFU (colony forming units) of clinically relevant microbes at 100x lower level of antimicrobial silver compared to other dressings.

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Biocompatibility

The biocompatibility profile of the Microlyte™ Ag VET wound dressing was assessed in accordance with ISO-10993: Biological Evaluations of Medical Devices. The biocompatibility test results demonstrate that Microlyte™ Ag wound dressing is biocompatible and safe for for use in management of partial and full thickness wounds including pressure ulcers, venous ulcers, diabetic ulcers, first and second degree burns, abrasions and lacerations, donor sites and surgical wounds, and debrided and grafted partial thickness wounds.

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Product Specifications

Microlyte™ Ag VET wound dressings are individually packaged in a sterile foil pouch. Supplied in boxes of individually packaged sterile dressings. Sterilization by E-beam radiation. Sterility is guaranteed unless pouch is damaged or opened. Single use only.

REF. 99000- 2 inch x 2 inch (5 cm x 5 cm)
REF. 99001- 4 inch x 4 inch (10 cm x 10 cm) (COMING SOON)

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Indications for Use

Microlyte™ Ag VET wound dressing is indicated for the management of veterinary wounds such as partial and full thickness pressure ulcers, first and second degree burns, abrasions and lacerations, and surgical wounds. Microlyte™ Ag VET wound dressing may be used over debrided and grafted partial thickness wounds.

Chronic Wounds

Trauma, Pressure Ulcers

Surgical Wounds

Surgical Incisions, Reconstruction Surgery

Burns

First and Second Degree Burns

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Product Application

The MicroLyte™ Ag wound dressing is easy to apply. Once removed from its pouch and placed on a moist wound bed, the MicroLyte™ Ag dressing immediately begins to hydrate and conform to the fine contours of the wound bed. Within seconds, the dressing has completely adhered to the wound and can be covered with the secondary dressing preferred for a given wound.

Veterinary Cases

A male domestic short-haired cat presented with a hock wound and fracture. There was significant devitalization of the soft tissues. The hock was repaired by tarsal arthrodesis and the wound was treated by conventional wound care and bandaging. Five months after treatment the wound remained open and had tripled in size after application of a hydrocolloid dressing. Previous management practices were resumed with wet to dry dressings and Tris-EDTA-amikacin, and the wound returned to its previous size and static condition. Microlyte™ Ag was applied after wound debridement and reapplied on Days 10 and 17. There was no evidence of discomfort on applying Microlyte™ Ag. The wound responded dramatically to application of this dressing in terms of both wound effusion and size, resulting in rapid and complete resolution of a chronic wound of previous 5-month duration.

A 2-year old female bulldog presented with a fracture after being hit by a car. The facture was repaired by tarsal arthrodesis. Significant surgical wound dehiscence and infection resulted. The infected wound was treated for two weeks with wound debridement, conventional dressings, along with retrograde intravenous and systemic antibiotics. Treatments were ineffective and the wound condition worsened revealing the bone fixation device. MicrolyteAg was applied and within one day, the soft tissue began to envelop the bone plate. By Day 3, the soft tissue had almost completely covered the bone plate. The most recent follow-up was on Day 13, where the wound showed healthy granulation tissue.

An 8-year old Rottweiler presented with an ulcerated elbow hygroma. The wound was treated for 2 months with padding, antibiotics, and pressure offloading with little progress. MicrolyteAg was applied to the wound and within 16 days, the wound had completely closed and all that remained was a small amount of eschar.

A 10-year old Irish Wolfhound presented with a chronic pressure sore over the ischial tuberosity. The sore was treated for over 3 months with little progress using conventional wound care techniques and donut pads for off-loading. MicrolyteAg was applied and after 14 days, the pressure sore had fully resolved with only a little eschar still present at the wound site.

An 8-year old Rottweiler presented with an ulcerated elbow hygroma. The wound was treated for 2 months with padding, antibiotics, and pressure offloading with little progress. MicrolyteAg was applied to the wound and within 16 days, the wound had completely closed and all that remained was a small amount of eschar.

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